Dysregulation of Mfn2 and Drp-1 proteins in heart failure
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چکیده
منابع مشابه
Deregulation of Mitochondria-Shaping Proteins Opa-1 and Drp-1 in Manganese-Induced Apoptosis
Mitochondria are dynamic organelles that undergo fusion and fission processes. These events are regulated by mitochondria-shaping proteins. Changes in the expression and/or localization of these proteins lead to a mitochondrial dynamics impairment and may promote apoptosis. Increasing evidence correlates the mitochondrial dynamics disruption with the occurrence of neurodegenerative diseases. Th...
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BACKGROUND The peripheral and central chemoreflexes are important autonomic mechanisms for regulating breathing and cardiovascular function. Although pathological inflammatory infiltration of the peripheral chemoreceptors and central nervous system has been reported in Chagas' disease, functional evaluation of chemoreflexes has not yet been performed. METHODS AND RESULTS The hypothesis that c...
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ژورنال
عنوان ژورنال: Canadian Journal of Physiology and Pharmacology
سال: 2014
ISSN: 0008-4212,1205-7541
DOI: 10.1139/cjpp-2014-0060